Have recent concerns about your skin led you to search for photodynamic therapy (PDT)? Are you looking for what it actually is and how it works? Can PDT help you? You’ve come to the right place to find out. PDT is a proven, non-invasive treatment that targets precancerous skin cells before they develop into something more serious.
This guide will discuss what photodynamic therapy involves, how it works, and what you can expect during and after treatment.
What Is Photodynamic Therapy (PDT)?
There are two steps to photodynamic therapy. First, a solution (such as aminolevulinic acid or methyl aminolevulinate) is applied to your skin. Then, after a brief waiting period, a specific wavelength of light activates the solution, producing reactive oxygen species that selectively target and eliminate precancerous cells.
Please note that PDT is not the same as the “red light therapy” you might see in wellness or beauty settings. PDT is an FDA-approved medical treatment specifically designed to address actinic keratoses and help prevent the progression to skin cancer.
How Does Photodynamic Therapy Work?
Understanding the process can help you feel more prepared and confident about your treatment.
Preparation
To prepare your skin, ensure it is thoroughly cleansed. A photosensitizing solution will then be applied to the treatment area. This solution is left on for about 60 to 90 minutes, giving it time to absorb into the abnormal cells.
Light Activation
Once the solution has been absorbed, your skin is exposed to either blue or red light. Blue light is intended for superficial lesions and typically requires about 16 minutes of exposure. Red light penetrates deeper into the skin and may be used for thicker lesions or more advanced precancerous conditions.
During this time, the light activates the photosensitizer, creating reactive oxygen species that destroy the targeted cells while sparing healthy tissue.
Post-Treatment Care
After your treatment, you can expect the area to appear red or feel tender—similar to a mild sunburn. As your skin heals, you may also see some peeling. These symptoms usually resolve within a few days to a week.
Your skin will remain photosensitive for the following 48 hours, so it’s important to remember to avoid direct sunlight during this time. Wearing protective clothing and staying indoors when possible is essential.
What Conditions Can PDT Treat?
PDT is primarily used to treat:
Actinic Keratoses (AKs): These are rough, scaly patches caused by long-term sun exposure. They’re considered precancerous because they can develop into skin cancer if left untreated.
Superficial Basal Cell Carcinoma: In some cases, PDT can be used to treat early-stage basal cell carcinoma.
Field Cancerization: This refers to areas with multiple sun-damaged spots that have the potential to become cancerous over time.
Benefits of Photodynamic Therapy
PDT is an accessible option with multiple benefits that make it an appealing choice for treating precancerous skin lesions:
- Non-invasive: Unlike surgery or cryotherapy, PDT doesn’t require cutting or freezing.
- Targeted treatment: It destroys abnormal cells while preserving healthy tissue.
- Minimal scarring: Most patients experience little to no scarring after treatment.
- Reduced future risk: PDT may help lower the likelihood of new lesions forming in treated areas.
Taking the Next Step
Photodynamic therapy is a safe and effective way to treat precancerous lesions and protect your skin. If you have concerns about actinic keratoses or other sun-related skin changes, reaching out to a dermatologist is a great starting point.
At Utah Valley Dermatology, we’re here to guide you through every part of your treatment journey with care and expertise. If you’re considering PDT or want to learn more about protecting your skin, explore our range of clinical skincare products designed to support healthy skin.Â
Contact us today to schedule a consultation and learn how PDT can help keep your skin at its best.
